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Despite the severe impact on individuals and society, there are no approved treatment options

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Its key to individualize care, as skin reacts uniquely based on genetics, lifestyle, and health history

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doi: 10.3390/ijms221910733 55 RahmanM

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During the process of melanogenesis, hydroxylation of L-tyrosine to form L-3,4-dihydroxyphenylalanine (L-DOPA) is the rate-limiting step of the whole process, which is catalyzed by TYR

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doi: 10.5534/wjmh.190009 43 OrgEMehrabianMParksBWShipkovaPLiuXDrakeTAet al

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